Interesting topic. I recently added a prologue to my book Winter's Queen, from the POV of the villain -- it's the only time the reader gets his POV for the whole book.
So far. This could change.
I think the idea of a prologue-only antagonist POV could be really interesting, but it might be neat if you brought it in for the first time later in your book (depending on whether that works for your story). It could really throw your readers for a loop, in a good way. I remember the first time I read a Cersei chapter in A Song of Ice and Fire, and how awesome it was. Getting into her head didn't make her any more sympathetic or any less of an antagonist, but it did help me understand her, and that can only be a good thing.
Whatever you decide, the fact that your antagonist is developed enough that they could carry their own chapters is awesome!
That your antagonist cuts to the chase!
I remember the first time I read a Cersei chapter in A Song of Ice and Fire, and how awesome it was. Getting into her head didn't make her any more sympathetic or any less of an antagonist, but it did help me understand her, and that can only be a good thing.
... I fear I may be biting off more then I can chew if I go this route.