I saw this today and thought it might be worth a look for those of you going the self-publishing route. At the moment, I don't have a dog in the hunt, so I can't really offer much insight about what I think is the "best" road. Maybe this blog post might help some people who are on the fence at the moment.
Five Mistakes KILLING Self-Published Authors | Kristen Lamb's Blog
Five Mistakes KILLING Self-Published Authors | Kristen Lamb's Blog